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 Summary table of ongoing studies

GPA on prednisone for maintenance

TAPIR (website)

Relapsing non-severe GPA


Flaring systemic GPA or MPA


Skin vasculitis

ARAMIS (treatment), CUTIS (biopsy)


VCRC cohorts (any time)


VCRC/VPPRN contact registry (any time)


DCVAS (<2 years)


CanVasc database (any time, in CanVasc centers)


BrainWorks (for children and adults)

 To read more information on each study, click on the name on the study when a link is available and/or read below.

NOTE (1 October 2016): Inclusions in the PEXIVAS study are closed (704 patients enrolled worlwide). Treatment and follow-up of enrolled patients are ongoing. First results expected in early 2018. Visit the official trial website HERE .

If you still need more detail on these studies or if you think that one of your patients could be eligible for any of this study, do not hesitate to contact us as well (


DCVAS is a non interventional study conducted under the combined aegis of the EUVAS, VCRC and the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) for the establishment of Diagnostic and new Classification Criteria for Primary Systemic Vasculitis (DCVAS).

There are currently no criteria to help doctors make a diagnosis of vasculitis when a patient presents with these non specific symptoms and they are reliant on previous experience and disease definitions. One of the aims of this project is to develop diagnostic criteria for the primary systemic vasculitides (granulomatosis with polyangiitis (Wegener's), microscopic polyangiitis, Churg Strauss syndrome, polyarteritis nodosa, giant cell arteritis, Takayasu arteritis). The investigators will do this by studying a large group of patients with vasculitis and comparing them to a large group of patients that present in a similar way, but do not have vasculitis. By comparing the 2 groups a list of items will be created to differentiate between vasculitis and 'vasculitis mimics'. A total of 3600 patients with vasculitis or vasculits 'mimics' are needed.

The second aim is to update the current classification criteria. Classification criteria are used to group patients into different types of vasculitis, once a diagnosis of vasculitis has been made, and are useful for studying patients in clinical trials with similar or identical diseases. The current classification criteria (American college of Rheumatology 1990 criteria) were developed 20 years ago, before the availability of some important diagnostic tests (e.g. antineutrophil cytoplasmic antibodies [ANCA]), and are now not consistent with some of the current disease definitions. Therefore to progress future research in vasculitis, it is important that the classification criteria are updated. For this study, 260 patients with each of the 6 types of vasculitis will be recruited and compared with 1300 controls (patients with the 5 other types of vasculitis), in order to determine the optimal combination of symptoms, signs and investigations that classify each person into the appropriate group.

It is an international study and several Canadians centers (all part of CanVasc) are participating, including London, Hamilton, Ottawa, Calgary and Toronto.

Click for here for more information or, alternatively, here.

Click here to download the trial text.

Click here to download to the record form (CRF).


This Web Page was updated the 27 October 2017 by Dr. Christian Pagnoux